Regeneron pauses drug trial on sickest – Home Health Choices
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Doctors, nonetheless, warn towards the follow. According to Dr Kabir Sardana, professor of dermatology at Ram Manohar Lohia (RML) hospital in New Delhi, they’ve come throughout healthcare employees utilizing the drug as a preventive creating pores and skin issues corresponding to raised itchy eruptions, swelling of face, itching of physique, itching of palms and soles, and rash involving the trunk.
“It was a chance finding. We received six patients, all of them healthcare workers managing Covid-19 patients, who complained about skin problems. Tests showed four of them had developed the problem due to HCQ use while two others due to other factors,” Dr Sardana advised TOI.
He added that after they investigated additional, it was discovered that quite a lot of sufferers who had been reporting with comparable pores and skin issues additionally had a historical past of taking HCQ with out prescription. It took practically two to 3 weeks for the pores and skin response to subside. Patients with extreme itching required oral steroids, the physician stated.
Dr Sardana stated healthcare employees taking HCQ must be conscious that even a weekly dose — accredited by Indian Council of Medical Research — could cause pores and skin rash. “If this is not treated properly, the skin problems can aggravate and cause serious health issues,” he added.
The outcomes of the examine carried out by RML on the side-effects of HCQ use in healthcare employees has been printed within the Journal of Dermatological Treatment. “While we will not debate on the merits and demerits of HCQ prophylaxis, it is pertinent to decide on whether the drug should be stopped or continued when side-effects are seen,” the examine states.
On June 17, World Health Organization (WHO) introduced that the HCQ arm of the Solidarity Trial to seek out an efficient Covid-19 therapy was being stopped. The United Nations physique took the choice primarily based on the findings of a UK examine that confirmed that the usage of this drug didn’t end in discount of mortality of hospitalised sufferers, compared with commonplace of care.
“The decision to stop hydroxychloroquine’s use in the Solidarity Trial does not apply to the use or evaluation of hydroxychloroquine in pre- or post-exposure prophylaxis in patients exposed to Covid-19,” WHO stated.